Brain Development and Health
In this category, you will find studies about the growth, development and well-being of children and teenagers with HIV infection or HIV-exposure over time. We are interested in whether the virus or its treatments affect youth’s brain development, learning, emotions or behavior. We also want to understand what role a child’s environment can play in helping or slowing development after HIV- exposure or infection.
Mental Health Diagnoses, Symptoms, and Treatment in Youth Living with PHIV
Adolescents with perinatal HIV (PHIV) or perinatal HIV exposure but uninfected (PHEU) may be at risk for
behavioral or emotional challenges. But they may not receive treatment. In our study, we wanted to see how many youth in PHACS experienced these challenges and how many were getting treatment. We also wanted to find out if there were things in their lives that made it more likely for them to experience these problems.
Medication Adherence for Youth Living with Perinatal HIV
Some youth born with PHIV may struggle with taking their HIV medications as prescribed on their own, which is important for when they become adults. We wanted to know whether their skills with self-care, planning and thinking ahead, and independent functioning helped them take their medication.
Local Shape Changes in the Brain in Youth Born with HIV
People living with HIV may have changes in how parts of the brain are shaped. We wanted to know whether youth born with HIV have changes in the shape of their brains and whether the changes were related to HIV. We also wanted to know if the brain shape changes affected their memory and problem-solving skills.
Learning and Memory in Children and Adolescents with Perinatal HIV
Memory, Attention, and Learning in Youth Born with HIV
How HIV Affects Long-Term Mental Function in Youth
In this study, we compared the learning and everyday functioning skills of infected and uninfected youth born to mothers with HIV. We also examined whether having HIV or an early AIDS diagnosis (an AIDS-illness at some point in their lives) made a difference in how well youth learned those skills.
How Blood Flow Affects Brain Function in Youth with HIV
Mental Health and Substance Use in Mothers Living with HIV
Safety of Baby Exposures to HIV Medicines and Outcomes
In this study, we wanted to see whether exposure to HIV medicines affects babies born to mothers with HIV in their first year of life. We gave the babies a test at one year old to see how well they were doing in five key developmental areas. We compared the babies whose mothers took HIV medicines while pregnant to the babies whose mothers who did not take HIV medicines while pregnant.
This publication was a collaboration between the Brain Development and Mental Health and Maternal Exposures Working Groups.